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Chemotherapy for a Brain Tumor

Chemotherapy (chemo) is a way of treating cancer with medicine. It may be given as a single medicine or a combination. There are many chemo medicines and combinations.

Chemo may be used alone or along with surgery and/or radiation therapy.

Here you can learn what chemo does, how it's given, and how to cope with common side effects.

Healthcare provider caring for man having infusion treatment.
Your IV treatment may last up to 8 hours, depending on the number of drugs given.

How chemotherapy works

Both normal and cancer cells grow and divide. But cancer cells grow and divide out of control. And they can spread to other parts of the body. Chemotherapy kills fast-growing cells by disturbing their life cycle. But it does this to normal cells as well as cancer cells. Because of this, chemo can cause side effects. Fast-growing cells are most affected. This includes cells in the hair, digestive system, and blood.

How chemotherapy is given

Chemotherapy is given in cycles. You have periods of rest between the days that chemo is given. This allows your body to recover and build healthy cells between treatments. You can get chemo for a brain tumor in many ways, such as:

  • By injection into your blood through a vein or artery (IV)

  • Injected into the spinal canal and cerebrospinal fluid (intrathecal)

  • As a pill you take by mouth

  • As wafers that are put in the brain at the parts of the tumor that can't be removed (this is done during surgery)

Coping with side effects

Chemotherapy can cause side effects in different parts of your body. Below are some common short-term side effects and tips to help control them.

For fatigue

  • Eat a healthy diet and drink plenty of fluids.

  • Try to not do too much. Get help with chores.

  • Rest as needed.

  • Stay active. Regular exercise can ease fatigue.

For nausea or vomiting

  • Take anti-nausea medicine as soon as you feel queasy.

  • Eat small meals and snacks during the day.

  • Stay away from strong smells.

For diarrhea

  • Drink more liquids. Include sports drinks which help replace lost electrolytes.

  • Switch to a low-fiber diet, like a BRAT diet. This is a diet of bananas, rice, applesauce, and toast.

  • Don't have caffeine, greasy food, spices, beans, or raw fruits and vegetables.

  • Call your healthcare provider if the diarrhea doesn’t go away in 24 hours or is severe.

For low blood cell counts

A low white blood cell count makes your body less able to fight infection. If you have a low white blood cell count:

  • Wash your hands often.

  • Stay away from crowds and people who are sick.

  • Watch for signs of infection, like fever, swelling, redness, cough.

A low platelet count increases the risk of bleeding and bruising. If you have a low platelet count:

  • Limit activities that could cause cuts or bruising.

  • Brush your teeth with a very soft brush and ask your doctor if it's okay to floss.

  • Blow your nose gently.

A low red blood cell count (anemia) can make you very tired and pale and can make you short of breath. If you have anemia:

  • Get plenty of rest.

  • Limit activities.

  • Get help with daily tasks.

For hair loss

  • Ask your healthcare team if you are likely to lose hair. Not all chemotherapy medicines cause hair loss.

  • Cut your hair short to make hair loss feel less extreme. Or you can choose to shave your head.

  • Be gentle when washing your hair.

  • Consider wearing a wig, hat, or scarf.

For mouth sores

  • Brush your teeth after meals to keep your mouth clean and prevent infection. Use a soft toothbrush.

  • Rinse with salt and soda water. Dissolve ¼ tsp of baking soda and 1/8 tsp of salt in 1 cup of water. Swish and spit as often as you like.

  • Eat foods that are soft and easy to swallow.

Possible long-term side effects

Possible long-term side effects depend on the chemo medicines used. They can include:

  • Infertility

  • Organ damage (like your heart, lungs, kidneys, or bladder)

  • Hearing loss

  • Vision changes

  • Numbness and tingling in the hands and feet (peripheral neuropathy)

  • Changes in your hormone balance

Talk with your healthcare team about the chemo medicines you take and the side effects you should watch for. Some of these may not cause problems until many years after treatment.

Working with your treatment team

Your cancer treatment team will talk with you about the possible side effects linked to your chemotherapy medicines. Tell them about any changes you notice. Most side effects can be treated and some can even be prevented.

Ask your healthcare provider what signs to watch for and when to call. Know how to get help after office hours and on weekends and holidays.

Online Medical Reviewer: Kimberly Stump-Sutliff RN MSN AOCNS
Online Medical Reviewer: Louise Cunningham RN BSN
Online Medical Reviewer: Richard LoCicero MD
Date Last Reviewed: 6/1/2020
© 2000-2022 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.